
方冠宇,博士,特聘副教授,從事傳統發酵食品中的微生物群落結構、功能及其适應性進化等方面研究。自2023年7月入職來主持國家自然科學基金項目1項,發表SCI/EI論文25篇。研究成果對推動傳統發酵食品的生産技術創新、提升産品品質以及提高生産效率起到了一定作用。擔任浙江省團隊科技特派員首席專家,浙江省調味品協會理事,Food Quality and Safety、Modern Agriculture和Grain & Oil Science and Technology期刊青年編委,The ISME Journal、Journal of Environmental Sciences、Future Microbiology、Sustainable Microbiology、《食品工業科技》 等多個SCI / EI期刊的審稿人。
研究方向:
(1)傳統發酵食品中微生物生态學(群落的組裝、進化、互作)及其代謝潛能;
(2)利用基因組學和比較基因組學探究微生物生境适應性進化機制及代謝特征;
(3)解析病原微生物及其抗生素耐藥性對人類健康風險和進化、傳播機制研究。
主要科研項目:
[1] 國家自然科學基金青年項目(32401323),環境微生物在釀醋微生态系統中的适應性分子機制,2025年01月至2027年12月,30萬元,主持
[2] bv伟德官方网站人才啟動項目(2024LFR050),氮源添加對黃酒品質影響的微生物學機制解析,2024.04-2027.03,15萬元,主持。
[3] 國家重點研發計劃項目(2024YFF1105500),糧食收儲質量提升關鍵技術研究與産業化示範,2024年12月至2027年11月,2000萬元,參與
發表的主要論文:
[1] Fang G-Y*, Mu X-J, Huang B-W, Jiang Y-J*. Monitoring longitudinal trends and assessment of the health risk of Shigella flexneri antimicrobial resistance[J]. Environmental Science & Technology, 2023, 57(12): 4971-4983. (中科院一區Top,IF5 years:11.6)
[2] Fang G-Y*, Wu F-H, Mu X-J, Jiang Y-J, Liu X-Q*. Monitoring longitudinal antimicrobial resistance trends of Staphylococcus aureus strains worldwide over the past 100 years to decipher its evolution and transmission[J]. Journal of Hazardous Materials, 2024, 465: 133136. (中科院一區Top,IF5 years:11.9)
[3] Fang G-Y*, Liu X-Q, Jiang Y-J, Mu X-J, Huang B-W. Horizontal gene transfer in activated sludge enhances microbial antimicrobial resistance and virulence[J]. Science of The Total Environment, 2024, 912: 168908. (中科院一區Top,IF5 years:8.6)
[4] Fang G-Y, Mu X-J, Huang B-W, Wu G-Z, Jiang Y-J*. Fungal biodiversity and interaction complexity were the important drivers of multifunctionality for flavor production in a spontaneously fermented vinegar[J]. Innovative Food Science & Emerging Technologies, 2023, 83: 103259. (中科院一區Top,IF5 years:6.5)
[5] Fang G-Y, Chai L-J*, Lu Z-M, Zhang X-J, Xu H-Y, Wang S-T, Shen C-H, Shi J-S, Xu Z-H*. Comparative genomics of Clostridium tyrobutyricum reveals signatures of environment-specific adaptation and metabolic potentials[J]. Food Bioscience, 2024, 61: 104691.(中科院一區Top,IF5 years:5.1)
[6] Fang G-Y, Chai L-J, Zhong X-Z, Jiang Y-J*. Deciphering the succession patterns of bacterial community and their correlations with environmental factors and flavor compounds during the fermentation of Zhejiang rosy vinegar[J]. International Journal of Food Microbiology, 2021, 341: 109070. (中科院一區Top,IF5 years:5.0)
[7] Fang G-Y*, Liu X-Q, Mu X-J, Huang B-W, Jiang Y-J. Distinct increase in antimicrobial resistance genes among Vibrio parahaemolyticus in recent decades worldwide[J]. Chemosphere, 2023, 340: 139905. (中科院二區Top,IF5 years:7.7)
[8] Fang G-Y, Chai L-J, Zhong X-Z, Lu Z-M, Zhang X-J, Wu L-H, Wang S-T, Shen C-H, Shi J-S, Xu Z-H*. Comparative genomics unveils the habitat adaptation and metabolic profiles of Clostridium in an artificial ecosystem for liquor production[J]. mSystems, 2022, 7(3): e00297-22. (中科院二區Top,IF5 years:6.1)
[9] Jiang J-J, Fang G-Y*, Wu C-L, Wang P, Zhang Y-Z, Zhang C, Wu F-H, Shan Z-C, Liu Q-R, Liu X-Q*. The Addition of Glutamine Enhances the Quality of Huangjiu by Modifying the Assembly and Metabolic Activities of Microorganisms during the Fermentation Process[J]. Foods, 2024, 13(17): 2833. (中科院二區,IF5 years:5.1)
[10] Qiu Z-Z, Wu F-H, Hu H, Guo J, Wu C-L, Wang P, Ling J-G, Cui Y, Ye J, Fang G-Y*, Liu X-Q*. Deciphering the Microbiological Mechanisms Underlying the Impact of Different Storage Conditions on Rice Grain Quality[J]. Foods, 2024, 13(2): 266. (中科院二區,IF5 years:5.1)
研究成果(獎項/專利/專著等):
[1] 一種機械攪拌法生産玫瑰醋的方法, 2020-11-10, 中國,ZL201810025250.9
[2] 一種黑棗露酒及其制備方法,2024-02-06,中國,ZL2010061197.5
[3] 一種固态發酵黑棗蒸餾酒及其制備方法,2023-09-19,中國,ZL202010800528.2
[4] 一種機械攪拌法生産玫瑰醋的設備,2018-11-13,中國,ZL201820042426.7
[5] 泵回流法生産玫瑰醋的設備,2018-11-13,中國,ZL 201820042323.0
教學工作:
參與本科生《食品微生物學》、《中國糧食》等課程教學,研究生《現代食品微生物》等課程教學
聯系方式:
通訊地址:浙江省杭州市臨安區武肅街666号bv伟德官方网站東湖校區,郵編311300
電子郵件: fangguanyu@zafu.edu.cn